How is THC ∆8 different from THC Delta-9?
A distinct physical difference in the molecular structure of these two cannabinoids exists; however, I think the core of this question relates to feelings and perceptions. So far from the collective stories of our patrons, friends, budtenders, and my own personal experience, THC Delta-8 provides an energetic, playful, and intuitive high without the paranoia or anxiety that is sometimes caused by THC ∆9. The effects will vary based on the method of consumption that you choose. Because concentrations of THC ∆8 are low in raw flower, extracts can be used in combination with Cbd hemp flower to offer a little variation and facilitate the near instant relief associated with smoking cannabis. The terpenes and other cannabinoids from the flower amplify the effect of the THC ∆8, this effect is called the entourage effect. Strain specific THC Delta-8 cartridges and drops are blended with terpenes to target certain sets of desired effects. Indica terpene profiles are generally more sedative and sativa terpene profiles are more energetic.
On a molecular level, there is a variation in the bonding of the carbon atoms in the protein chains. The word “delta ∆” signifies a double bond. In a THC Delta-9 molecule the double bond is in the 9th slot of the protein chain and in the THC Delta-8 molecule it is in the 8th. Both THC Delta-8 and THC Delta-9 bind with the CB1 receptors in your brain to produce the psychoactive effects. THC Delta-8 will also bind with the CB2 receptors throughout your body. The CB2 receptors, when activated by THC ∆8, work to boost the immune system and help reduce inflammation throughout the body in a manner similar to CBD (1). This ability to bind to both types of cannabinoid receptors in the brain releases an interesting cocktail of neurotransmitters that help the body and mind work towards homeostasis.
What are the medical benefits of THC Delta-8?
One fundamental principle of medical cannabis that is often overlooked is that it sparks joy, enthusiasm, and hope in its users. The benefits of cannabis have always stretched beyond the physical. Studies show that many ailments are caused by stress (2). Personally, just about everyone I know that uses Cannabis on a regular basis, agrees that it helps them to chill out.
Many medications used to treat pain, anxiety, digestive and sleep disorders cause horrible side effects that create secondary problems. Cannabis is a natural alternative or supplement to these other medications. By using less of these prescription medications with their potentially dangerous side effects, one is definitely receiving a medical benefit from Cannabis.
The National Library of Medicine defines and codifies the THC Delta-8 molecule as an antiemetic, anxiolytic, analgesic, appetite stimulating, and neuroprotective cannabinoid (3). With the exception of being an anti anxiety cannabinoid (anxiolytic) THC ∆8 shares these same properties with THC ∆9. The special medical interest in THC Delta-8 is because the psychoactive properties of THC Delta-8 are geared differently and not quite as intense. This allows doctors to administer large amounts of THC Delta-8 to curb severe pain and nausea without causing total panic attacks.
How does THC Delta-8 affect appetite?
Institutional studies on THC Delta-8 are lagging behind with scientific proof. So far, feedback from customers that have tried our THC ∆8 products report having an enhanced desire to eat. We all know what regular marijuana can do to the appetite. Some strains will leave you cleaning out the fridge and others will not.
Raphael Mechoulam and his team initiated a study into the potential of THC ∆8 to alleviate vomiting and other digestive issues that occur from chemotherapy, especially in children. THC ∆8 is also an anti-anxiety cannabinoid. Larger doses of THC ∆8 can be given to children undergoing chemotherapy without worrying about the intense paranoia and anxiety that can sometimes accompany the psychoactive effects of THC ∆9 at the same large dose. The larger doses are required to induce the appetite and curb vomiting in the patients. Out of the 13 children in the original study, 100% of them stopped vomiting and were able to consume food (4).
Considering our personal experiences here at the Alpine Dispensary, stories from our customers, and studies like Mechoulam’s cancer study, we can conclusively say that THC Delta-8 stimulates the appetite and alleviates nausea in most cases. If it can help with the violent effects of chemotherapy on the digestive system, a little stomach ache should be easily obliterated and hangovers will disappear like the morning dew. Like every other cannabis product, ‘How?’ and ‘How Fast?’ are relative to the delivery method and an individuals tolerance to cannabinoids.
Will THC Delta-8 help with sleep issues?
Peer reviewed studies specifically related to THC Delta-8 in regards to sleep are relatively few and far between. Springer Science published a compilation of peer reviewed studies on Cannabis and Sleep (5). The studies found that synthetic derivatives of cannabinoids that have been turned into prescription medications and isolated cannabinoids like our THC ∆8 were less effective on sleep than using raw flower or other forms of extracts that preserve the entourage effect. The entourage effect emerges when cannabinoids are used in combination with each other and/or with other terpenes.
How is THC Delta-8 legal?
Our THC ∆8 comes from CBD rich Hemp containing less than .3% THC ∆9 and is federally legal. The definition of hemp found in Section 7606 of the 2014 Farm Bill is the same as the current definition of hemp found in 7 U.S.C. Section 5940 . The most up to date federal regulations related to hemp can be found in the Federal Register of the National Archives. The Georgia Farm Bill follows the federal precedent declaring in the GAC 2-23-3 and GAC 2-23-5 (6).
(3) ‘Federally defined THC level for hemp’ means a delta-9-THC concentration of no more than 0.3 percent on a dry weight basis, or the THC concentration for hemp defined in 7 U.S.C. Section 5940, whichever is greater.
(5) ‘Hemp’ means the Cannabis sativa L. plant and any part of such plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with the federally defined THC ∆9 level for hemp or a lower level.
Will THC ∆8 show up on a drug test?
Yes, the metabolites from THC ∆8 are similar to those of THC ∆9 and will trigger test results. If you are concerned about passing a drug test, we have plenty of CBD Isolate products that can help with pain, inflammation, anxiety, and sleep that are THC free.
Where does THC ∆8 come from? Why have I not seen it before?
THC ∆8 occurs naturally in cannabis plants at low levels. THC ∆9 and CBD are more abundant in cannabis plants and have similar medical benefits to THC ∆8. Raising THC ∆8 levels through selective breeding is many years away at best. No special incentive existed to manufacture THC ∆8 until CBD and its derivatives were removed from Schedule 1 status and legalized by the 2018 farm bill. The 2018 Farm Bill created a new potential market in consumers that want a legal cannabis buzz in states where cannabis prohibition limits the use of cannabis to strictly medicinal cases or bans its use entirely if the THC ∆9 concentration is higher than .3%. Processes to convert CBD into THC ∆8 were patented over 15 years ago. When the Farm Bill removed CBD from Schedule One status and legalized hemp derived CBD nationwide people were already waiting to expand THC ∆8 production and fill the market with the same great variety of products one would expect in the world of CBD.
Will THC Delta-8 get me “high” or “stoned”?
Yes, in fact it is recommended to avoid the operation of heavy machinery, driving a vehicle or performing other dangerous activities after consuming THC ∆8.
How much THC ∆8 does it take to feel the effects?
The answer to this question is relative to the method of delivery. When puffing on one of our THC ∆8 cartridges, go puff by puff until you get a feel for how THC ∆8 affects you personally. Take one puff and wait five minutes and set your own limitations based on your comfort level. When consuming our THC ∆8 gummies, most people start with one half of a gummy for people that don’t have a lot of experience with cannabis. Taking two half gummies an hour apart is not as strong as taking one whole gummy by itself. We recommend moderation until you fully understand the potential benefits of this powerful cannabinoid.
How many different products do you have that contain THC Delta-8?
Alpine Dispensary carries a variety of THC Delta-8 products. We have 22mg gummies in a 5 and 10 pack, six different strains of THC ∆8 Vape Cartridges with Indica, Sativa, and Hybrid terpene profiles. We have water soluble nano drops for rapid and precise delivery of THC Delta-8 and our THC Delta-8 Oil that can be used sublingually, as a vape additive or in cooking. Customer feedback on all of our products is appreciated. We will continue to innovate and respond to the requests of our valued patrons.
Oláh A, Szekanecz Z, Bíró T. Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges. Front Immunol. 2017;8:1487. Published 2017 Nov 10. doi:10.3389/fimmu.2017.01487
2. Salleh MR. Life event, stress and illness. Malays J Med Sci. 2008;15(4):9-18.
3. National Center for Biotechnology Information. PubChem Compound Summary for CID
2977, delta8-THC. https://pubchem.ncbi.nlm.nih.gov/compound/delta8-THC.
4. Abrahamov A, Abrahamov A, Mechoulam R. An efficient new cannabinoid antiemetic in
pediatric oncology. Life Sci. 1995;56(23-24):2097-2102. doi:10.1016/0024-3205(95)00194-b
5. Babson Kimberly A., Morabito, Danielle and Sottile, James. Cannabis, Cannabinoids, and
Sleep: A Review of the Literature. Springer Science + Business Media, 27 March 2017
6. Georgia House Bill 213: 2-23-3 and 2-23-5, http://www.legis.ga.gov/Legislation/
20192020/187562.pdf accessed: legis.ga.gov 8-30-2020.
Article Written By:
"Early in my working life, I joked with some people that one day I would make Mojo Coordinator an officially recognized job title. What does a Mojo Coordinator do? I stealthily and silently use my vision, intuition, diverse skillset and enhanced sensory perception to observe and facilitate seamless workflow, communication, productivity, efficiency and camaraderie."